http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-105802998-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-87 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-87 |
| filingDate | 2016-03-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2019-04-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2019-04-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-105802998-B |
| titleOfInvention | A kind of magnetic nano-balls and its preparation method and application of clad structure layer by layer |
| abstract | The invention discloses a kind of magnetic nano-balls and its preparation method and application of clad structure layer by layer.The magnetic nano-balls are made of kernel, middle layer and outer layer, are be combined with each other by electrostatic attraction effect between kernel and middle layer, between middle layer and outer layer；Kernel is cationic polymer modified ferriferrous oxide nano grain, and middle layer is the gene to be transfected being coated on the outside of kernel, and outer layer is the spermine-pulullan polysaccharide copolymer being coated on the outside of middle layer.The magnetic nano-balls are first in conjunction with kernel by gene to be transfected, then in conjunction with spermine-pulullan polysaccharide copolymer, so that gene to be transfected is tightly wrapped in magnetic nano-balls, gene are avoided to be degraded in transfection process；Spermine-pulullan polysaccharide can identify and be absorbed by mesenchymal stem cell, and further increase magnetic nano-balls enters born of the same parents' efficiency；Spermine-pulullan polysaccharide copolymer effectively reduces transfection security risk caused by stem cell to mesenchymal stem cell small toxicity. |
| priorityDate | 2016-03-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 39.