http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-105801560-B
Outgoing Links
Predicate | Object |
---|---|
classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y02P20-55 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D401-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07B57-00 |
filingDate | 2016-04-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2018-05-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2018-05-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CN-105801560-B |
titleOfInvention | A kind of synthetic method of the Rabeprazole metabolin of single configuration |
abstract | The invention discloses a kind of synthetic method of the Rabeprazole metabolin of single configuration, this method is obtained using Rabeprazole thioether as starting material through the reaction synthesis of five steps.The present invention by many experiments filters out optimal preparation process and reaction condition, and whole technological design is reasonable, workable, the Rabeprazole metabolin for the single configuration that the present invention is prepared, and chemical purity is up to more than 99%, and chiral purity>99.5%.The Rabeprazole metabolin for the single configuration that the present invention is prepared provides standard items for the metabolic mechanism research of Rabeprazole medicine, available for the metabolic process of the medicine in vivo is probed into, there is great application study value in CLINICAL PHARMACOKINETIS STUDY ON. |
priorityDate | 2016-04-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 69.