| abstract |
The invention discloses a method for preparing benzochromene derivatives represented by formula (I), and the benzochromene derivatives can be used as synthetic intermediates of medicines, such as synthetic intermediates of Velpatasvir. The method of the invention uses cheap and easy-to-obtain o-fluorohalogenated benzene as the initial raw material, provides a brand-new synthesis route for preparing benzochromene derivatives, has a high total yield in the whole reaction route, and is suitable for large-scale industrial production. |