http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-105801507-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D257-04 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D257-04 |
| filingDate | 2016-05-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2018-04-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2018-04-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-105801507-B |
| titleOfInvention | One kind 1（3 bromophenyls）The preparation method of 1H tetrazoles |
| abstract | The present invention relates to a kind of preparation method of 1 (3 bromophenyl) 1H tetrazoles, including：(1) 3 bromanilines, water and fluoborate aqueous solution are mixed, sodium nitrite in aqueous solution then is added dropwise under 0~5 DEG C of stirring, is added dropwise and is warmed to room temperature, continued stirring 1~2h of reaction, filter, obtain 3 bromophenyl diazonium tetrafluoroborates；(2) 1H tetrazoles, alkali, copper salt catalyst and stirring solvent are mixed at 5 DEG C~5 DEG C, then 3 bromophenyl diazonium tetrafluoroborates are added portionwise, 5 DEG C~6~8h of lower reaction is stirred at room temperature, extracted after the completion of reaction, be dry, boiling off solvent, recrystallization, to obtain the final product.The present invention shortens the reaction time, while improve yield using mantoquita as catalyst；Preparation method starting material is easy to get, and cost is low, and operation is simple, and reaction scheme is short, is easy to industrialized production, has a good application prospect. |
| priorityDate | 2016-05-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 63.