http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-105796494-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-0019 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-4422 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-1075 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-183 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P9-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-4422 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P25-28 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-107 |
| filingDate | 2016-04-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2019-10-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2019-10-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-105796494-B |
| titleOfInvention | A kind of Nimodipine sub micro-emulsion injection and preparation method thereof containing amino acid |
| abstract | The invention discloses a kind of Nimodipine sub micro-emulsion injection and preparation method thereof containing amino acid, it includes Nimodipine, oil for injection, injection phosphotide, coemulsifier, amino acid, glycerol and water for injection that it, which is formed, and wherein the content of amino acid is 0.01-3%.Protective agent present invention adds amino acid as Nimodipine; pass through the dihydropyridine ring in protection drug molecule; avoid dehydrogenation reaction; reduce the generation of Nimodipine catabolite; reduce Light absorbing impurty; the chemical stability for carrying medicine sub-micellar emulsion is improved, is effectively prevented due to impurity content height and existing genotoxic potential risk. |
| priorityDate | 2016-04-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 54.