http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-105777903-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K16-241 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K1-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K16-24 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K1-20 |
| filingDate | 2016-03-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2018-04-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2018-04-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-105777903-B |
| titleOfInvention | A kind of cation exchange chromatography method of adalimumab |
| abstract | The invention discloses a kind of method of the cation exchange chromatography of adalimumab, by adding urea and betaines surfactant in CEX multistep elution processes by the pollutant removal in the mixture comprising antibody and pollutant, polymer is set to be separated with antibody, hydrophobic interaction chromatography is then carried out, separated from contaminants effect is good；Chromatography process sample adjusts the acute variation for simply, avoiding pH value, and Content of polymer significantly reduces in final purified product. |
| priorityDate | 2015-03-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 45.