Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_fe511b4e57c11304f1eff2dd62fc86b5 |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07B2200-13 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D237-32 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D237-32 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-502 |
filingDate |
2015-12-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_caf8055ab3acde3df0e0ffaa0dcb29cb http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4ebad68039c27cbf1aa2ea08fa9c95bd http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_906f120fd04630b55c210a52a22d070f http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_38d268e4cd416167f6cca998e2c70ce8 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_daf9314d9e06096615450f9068e33d8e http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a7d6aac23c7484773b3cb499370c7303 |
publicationDate |
2016-07-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
CN-105777651-A |
titleOfInvention |
Crystal form of polyadenylate diphosphate ribosyltransferase inhibitor, preparation method and medical application thereof |
abstract |
The invention relates to a crystal form of a polyadenylic acid diphosphate ribosyltransferase inhibitor, a preparation method and a medical application thereof. Specifically related to poly(ADP-ribosyltransferase) (PARP) inhibitors namely 4‐[3‐(4‐cyclopropanecarbonyl‐piperazine‐1‐carbonyl)‐4‐fluoro‐benzyl]‐2H‐phthalazine‐ A new crystal form of 1-ketone, its preparation method, pharmaceutical composition and application in treating cancer. The new crystal form provided by the present invention has good reproducibility, is stable and easy to obtain, and is suitable for drug development. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/TW-I639593-B http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10662178-B2 |
priorityDate |
2015-01-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |