http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-105777573-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C231-02 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C235-34 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C231-02 |
| filingDate | 2016-05-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2018-01-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2018-01-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-105777573-B |
| titleOfInvention | The preparation method of N coumaric acyl dopamines |
| abstract | The invention discloses the preparation method of N coumaric acyl dopamines, and reactant dopamine hydrobromate, p-Coumaric Acid methyl esters and alkali are added in four round flask, add solvent, stirring, and thin-layer chromatography detection reaction terminates；Water stratification is added in reaction solution, then again plus ethyl acetate extraction, organic phase saturated common salt water washing, inorganic phase washs with watery hydrochloric acid, then with anhydrous sodium sulfate drying, filters, concentration, obtain slurry；Petroleum ether is added into above-mentioned slurry, is heated to reflux, cools down, stand, upper solution is poured out, then ethyl acetate is added into slurry, is stirred, is filtered, is dried, is obtained off-white powder product, identified through nuclear-magnetism, products obtained therefrom is N coumaric acyl dopamines.In the synthetic method of the N coumaric acyl dopamines of the present invention, direct one-step synthesis obtains final product, greatly reduces synthesis step number, so that production cost substantially reduces.And just because of the reduction of synthesis step number, so also facilitating the post processing work of reaction simultaneously, reduces purifying difficulty. |
| priorityDate | 2016-05-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 53.