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filingDate 2016-03-23-04:00^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 2018-03-27-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationDate 2018-03-27-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber CN-105754026-B
titleOfInvention Realize the application process that the film modified glycosaminoglycan of cell breaks up similar to thing and its synthetic method and its external evoked stem cell directional
abstract The invention discloses the application process that a kind of glycosaminoglycan for realizing that cell is film modified breaks up similar to thing and its synthetic method and its external evoked stem cell directional, the analog is inserted into cell membrane surface, and within the shorter cycle stem cell directional can be promoted efficiently to be divided into ripe neuronal cell.The glycosaminoglycan of phosphatide grappling prepares a kind of glycosaminoglycan similar to thing by Invertible ideal (RAFT) first similar to thing in the present invention, further realizes phosphatide of the glycosaminoglycan similar to thing using the phospholipid molecule of maleimation.The glycosaminoglycan of phosphatide, by the affinity interaction between phosphoester groups and cell membrane, glycosaminoglycan is incorporated into similar to thing the surface of stem cell, ripe neuronal cell is efficiently divided into so as to be more beneficial for promotion stem cell similar to thing.Building-up process of the present invention is simple, there is provided a kind of powerful means that can realize substantially any RAFT polymer phosphatide.
priorityDate 2016-03-23-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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