http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-105753834-B
Outgoing Links
Predicate | Object |
---|---|
classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07B2200-07 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D319-06 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D319-06 |
filingDate | 2016-03-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2018-08-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2018-08-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CN-105753834-B |
titleOfInvention | A kind of synthetic method of rosuvastain calcium key chiral intermediate |
abstract | The invention discloses a kind of synthetic methods of rosuvastain calcium key chiral intermediate, belong to the synthesis technical field of medicine intermediate.Technical scheme of the present invention main points areļ¼ .Present invention process route not only avoids the use of 3 3-hydroxyethyl butyrate of expensive drug (R) 4 bromine, and it is effectively improved since the use of chiral catalyst makes the ee of product be worth to, and synthetic method raw material is simple and easy to get, route is easy to operate, reproducible and yield is very high, is suitble to industrialized production. |
priorityDate | 2016-03-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 154.