http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-105749288-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-1664 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-46 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-385 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-1611 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-46 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-38 |
| filingDate | 2016-02-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2019-05-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2019-05-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-105749288-B |
| titleOfInvention | The mesoporous silicon dioxide micro-sphere and its synthetic method of a kind of monitoring of near infrared light, controlled drug release |
| abstract | The invention belongs to nano meter biomaterial technical field, mesoporous silicon dioxide micro-sphere and its synthetic method that specially a kind of near infrared light monitoring, controlled drug discharge.Mesoporous silicon dioxide micro-sphere of the invention is multilayered structure: most kernel is a smooth nano SiO 2 particle, for adjusting microspherulite diameter and load near-infrared nanocrystalline body, these near-infrared nanocrystalline bodies are under the near infrared light excitation of certain wavelength, lower transformation can occur, that is, issue the near infrared light of specific wavelength；Secondary outer layer is one layer of smooth silica shell, for fixing and protecting the near-infrared nanocrystalline body of internal layer；Outermost layer is mesoporous silicon oxide shell, for the quencher molecule of load target drug and near infrared light nanocrystal, and connects or coat responsive polymer, to realize that controlled drug discharges.The controlled release of drug not only may be implemented in silicon dioxide microsphere provided by the invention, and the means that can be imaged by biological living monitor the burst size of drug and the metabolic condition of carrier. |
| priorityDate | 2016-02-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 113.