http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-105732524-A

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assignee http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_0ec795b989cd080992372eb9681ea624
classificationIPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D241-24
filingDate 2014-12-10-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8e115baf46a62bae5bb579a3bfd16c2d
publicationDate 2016-07-06-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber CN-105732524-A
titleOfInvention A preparing method of 6-bromo-3-hydroxy-2-pyrazinamide
abstract The invention belongs to the field of chemical synthesis and particularly relates to a preparing method of 6-bromo-3-hydroxy-2-pyrazinamide. The method adopts methyl 3-hydroxy-2-pyrazinecarboxylate as an initial raw material and includes converting the raw material into methyl 6-bromo-3-hydroxy-2-pyrazinecarboxylate, and performing aminolysis, so that the 6-bromo-3-hydroxy-2-pyrazinamide is prepared with a high yield through simple and convenient operation. The method is advantageous in that the methyl 3-hydroxy-2-pyrazinecarboxylate which is low in price and convenient to purchase in the market is adopted as the initial raw material, the preparing method is simple, convenient and feasible, adopted solvents are wide in range and easily removable, the yield is high, and the method can be used for industrial production.
isCitedBy http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-112851589-A
priorityDate 2014-12-10-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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