http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-105726554-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-7048 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P1-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P1-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-7048 |
| filingDate | 2016-02-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2019-05-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2019-05-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-105726554-B |
| titleOfInvention | Dioscin is preparing the application in acute gastrointestinal damage protection drug |
| abstract | Present invention discover that Dioscin has acute gastrointestinal damage protective effect, it can be used for being made acute gastrointestinal damage protection drug.MTT and morphological observation prove that Dioscin has significantly protective effect to GES-1, Caco-2 and IEC-6 cell of hypoxia in vitro reoxygenation.Meanwhile Dioscin increases with apparent downward effect MDA caused by acute gastrointestinal damage and MPO, has obvious up-regulation effect to the reduction of T-SOD and GSH-PX.After Dioscin is intervened, gastric mucosal damage index after ischemical reperfusion injury increases, gastric mucosal erosion bleeding, phenomena such as local gland structure disorder, is obviously improved, and the villus shedding after ischemical reperfusion injury is obvious, phenomena such as telangiectasis, body of gland is impaired obvious, partially visible bleeding ulcer is obviously improved.According to clinical application demand, drug can be made using Dioscin as single active ingredient, can also be shared with other drugs and compound preparation is made. |
| priorityDate | 2016-02-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 142.