http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-105709233-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-34 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-704 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K41-0052 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-704 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K41-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-34 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-04 |
| filingDate | 2016-01-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2019-01-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2019-01-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-105709233-B |
| titleOfInvention | A kind of magnetic targeting nanodiamond drug and its preparation method and application |
| abstract | The present invention provides a magnetic targeting nanodiamond medicine and a preparation method and application thereof. The carboxylated magnetic Fe 3 O 4 and nanodiamonds (ND) were formed into a magnetic nanodiamond composite (Fe 3 O 4 ‑PLL‑ND) under the action of the coupling agent polylysine (PLL); Anticancer drug doxorubicin (DOX), obtained magnetic targeting nanodiamond drug (Fe 3 O 4 ‑PLL‑ND‑DOX); under the action of an external magnetic field, the magnetic targeting drug was combined with human cervical cancer (HeLa) cells It can target and inhibit tumor growth. Using tumor-bearing mice as a model to study its magnetic targeting effect in vivo, it shows that it can target and localize to tumor sites. The magnetic targeting nanodiamond drug can be used in the preparation of magnetic targeting antitumor drugs. |
| priorityDate | 2016-01-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 52.