| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_1e99fd6c617f0e7f638fd24c636e8bd2 |
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http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2319-55
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y02A50-30
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2039-575
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Y204-01 |
| classificationCPCInventive |
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http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K39-095
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http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K39-08
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http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-70
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http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K19-00 |
| classificationIPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12R1-01
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http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12R1-19
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12R1-42 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-74
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http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K39-104
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http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K39-08
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K19-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P31-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-48 |
| filingDate |
2014-11-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4c8beee48d764db4409cc872d2b22a7d
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_defd1f4ed049f8e2387559da74e57ff3
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_40373bd293e90c345f5e9c19f4d9330b
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d16371e972a1d9bfa47c8857b99cd9e5
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7952e67f50071384ea5b640b9a503856
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4953e975c9f3e5b7408360e7998059ae
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b79af17e6e12a97b31dffa8b231cf299
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_86086ad5657ff6071881cd5831b06873
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_41252f334416dab19817bb3af23ca38d
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1252d8dfe65a6b1c704758ee7e801fee
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6c90141323254dcfab2ad6a3f7db9ed8
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_40205ff540733157d9479cd0d98a9250 |
| publicationDate |
2016-06-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
CN-105695497-A |
| titleOfInvention |
Preparation method and application of a bacterial polysaccharide-modified recombinant fusion protein |
| abstract |
The invention discloses a preparation method and application of a bacterial polysaccharide-modified recombinant fusion protein. The invention discloses a preparation method of a bacterial polysaccharide-modified recombinant fusion protein. The recombinant fusion protein and Neisseria meningitidis O-oligosaccharide transferase PglL are co-expressed in bacteria with O-antigen ligase gene deficiency. The O-oligosaccharide transferase PglL of Seinococcus connects the bacterial polysaccharide or exogenous polysaccharide to the recombinant fusion protein to obtain the recombinant fusion protein modified by the bacterial polysaccharide. The recombinant fusion protein modified by the bacterial polysaccharide prepared by the method of the present invention is used to immunize mice to obtain specific antibodies against bacterial polysaccharide, and the recombinant fusion protein modified by this bacterial polysaccharide is used for the preparation of bacterial polysaccharide protein-binding vaccine, which can avoid Many problems in the cultivation of pathogenic bacteria can be improved, the uniformity and production efficiency of the vaccine can be improved, and the cost of vaccine preparation can be reduced. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-106511994-B
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-112501096-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-109420165-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-106511994-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-109420165-B
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-111909951-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-112457408-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-113403240-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-111909951-B
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-114277050-A |
| priorityDate |
2014-11-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |