http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-105693703-B

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classificationCPCAdditional http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C09K2211-1088
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classificationCPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N21-6486
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filingDate 2016-01-25-04:00^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 2018-12-25-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationDate 2018-12-25-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber CN-105693703-B
titleOfInvention A kind of novel Ratiometric fluorescent probe for the imaging of intracellular lysosomal pH
abstract The present invention provides a kind of novel Ratiometric fluorescent probes for the imaging of intracellular lysosomal pH, it is prepared with the following method: by the 1-(3-dimethylaminopropyl)-3-ethylcarbodiimide of a2,2mmol of a1,1mmol of 1mmol, the 1- hydroxy benzo triazole of 1.5mmol, the triethylamine of 2.2mmol and the N of 5mL, dinethylformamide is added in 50mL single-necked flask, it is stirred at room temperature 16 hours, filtering, drying;By obtained solid carry out column chromatographic purifying to get.Fluorescence probe prepared by the present invention can measure the pH in lysosome with the fluorescence intensity of quantitative detection different shape.
priorityDate 2016-01-25-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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