http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-105693605-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D215-46 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D215-46 |
| filingDate | 2016-03-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2017-12-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2017-12-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-105693605-B |
| titleOfInvention | A kind of method of asymmetric synthesis of optical voidness (R)/(S) chloroquine |
| abstract | The invention discloses a kind of method of asymmetric synthesis of optical voidness (R)/(S) chloroquine, using the chloroquinoline of 4 amino 7 and the pentanone of 5 diethylin 2 as initiation material, under the catalysis of chiral acid, optically pure chloroquine, the spatial configuration of the spatial configuration control product of chiral acid are obtained by asymmetric reduction amination.This method route is simple, raw material is easy to get, yield is higher, stereoselectivity is good, chiral construction cost is relatively low, simple to operate and green, is adapted to large-scale production. |
| priorityDate | 2016-03-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 92.