http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-105693598-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D211-74 |
| filingDate | 2014-11-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2017-12-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2017-12-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-105693598-B |
| titleOfInvention | A kind of method that iridium catalytic hydrogenation synthesizes 3 derivative of piperidone |
| abstract | A kind of method that iridium catalytic hydrogenation synthesizes 3 derivative of piperidone, its catalyst used is the triphenylphosphine complex of iridium.Reaction can be carried out under the following conditions, temperature：40‑60℃；Solvent：1,2 dichloroethanes；Pressure：20 50 atmospheric pressure；The ratio of substrate and catalyst is 100/l；Catalyst is the complex of (1,5 cyclo-octadiene) iridium chloride dimer and triphenylphosphine.The hydrogenation of 3 pyridone benzyl bromides can obtain 3 derivative of piperidone with excellent chemo-selective, and for highest yield up to 97%, the chemo-selective of ketone and alcohol is more than 20:1.The present invention is easy to operate, and raw material is easy to get, and chemo-selective is high, and yield is good, and an Atom economy, environment-friendly route are provided for a series of synthesis of 3 derivative of piperidone. |
| priorityDate | 2014-11-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 114.