http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-105687135-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-107 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-34 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-4535 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-0002 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-704 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-64 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-60 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-704 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-34 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-107 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-4535 |
| filingDate | 2016-03-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2019-09-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2019-09-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-105687135-B |
| titleOfInvention | A kind of heterozygous cancer target nano-micelle and application thereof |
| abstract | Disclosed by the invention is a kind of heterozygous cancer target nano-micelle and application thereof, the micella is mixed self assembly by polymer 1 and polymer 2 and is obtained, wherein, the water-wet side of polymer 1 and polymer 2 is respectively the polyethylene glycol block of Valine-Valine dipeptides, Raloxifene modification, and hydrophobic side is polyhistidine or Polyalanine.Be a kind of based on PepT1, ER be the nano-micelle targeted, hydrophobic anticancer drug can be wrapped up, in vitro study is shown, such micella stability is substantially better than non-heterozygous micella, simultaneously, such nano-micelle drug delivery system can be absorbed by the highly expressed tumor cells selectivity of PepT1, ER, and show selecting cell toxicity to such tumour cell, can be applied to prepare in neoplasm targeted therapy drug. |
| priorityDate | 2016-03-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 67.