http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-105669551-B
Outgoing Links
Predicate | Object |
---|---|
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D221-18 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-473 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D221-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 |
filingDate | 2015-12-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2018-04-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2018-04-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CN-105669551-B |
titleOfInvention | 7 benzo (c) acridines are to fluorobenzoyl amido thiocarbamide and its preparation method and application |
abstract | The invention discloses 7 benzo (c) acridines to fluorobenzoyl amido thiocarbamide and its preparation method and application, it is with structural formula: And application of the present invention in antitumor drug is prepared, injection, tablet, pill, capsule, suspending agent or emulsion is made with pharmaceutically acceptable auxiliary material combination;The present invention connects active group amide groups thiocarbamide in benzo (c) acridine female ring, introduces fluorine-containing group, strengthens the bioactivity of female ring structure by the principle of activity superposition.Antitumor activity in vitro shows that the compound has stronger inhibitory action to test tumour cell, antitumor drug or lead compound can be used as further to develop. |
priorityDate | 2015-12-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 90.