http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-105669551-A
Outgoing Links
Predicate | Object |
---|---|
assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_3935357f2393110e9394b6233f8fccb3 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D221-18 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-473 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D221-18 |
filingDate | 2015-12-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ae8e1c4305d7acf51bac48b9c86c3d97 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7ece37bef7f4c9d7d628be8f4aa337d5 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4f966749b7dc862f8bc2c56790646b59 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a1f8f8cdaeb160cad68ef278dacb5170 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ea389c8012498bcbf6b7d0d502957a15 |
publicationDate | 2016-06-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CN-105669551-A |
titleOfInvention | 7-Benzo(c)acridine p-fluorobenzamidothiourea and its preparation method and use |
abstract | The invention discloses 7-benzo(c)acridine-p-fluorobenzamidothiourea and its preparation method and application, which has a structural formula: And the application of the present invention in the preparation of antitumor drugs, combined with pharmaceutically acceptable auxiliary materials to make injections, tablets, pills, capsules, suspensions or emulsions; the present invention connects the active The group amidothiourea introduces a fluorine-containing group to enhance the biological activity of the parent ring structure through the principle of active superposition. The antitumor test in vitro shows that the compound has a strong inhibitory effect on the tested tumor cells, and can be further developed as an antitumor drug or a lead compound. |
priorityDate | 2015-12-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 30.