http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-105669551-A

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classificationCPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D221-18
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http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D221-18
filingDate 2015-12-02-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ae8e1c4305d7acf51bac48b9c86c3d97
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publicationDate 2016-06-15-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber CN-105669551-A
titleOfInvention 7-Benzo(c)acridine p-fluorobenzamidothiourea and its preparation method and use
abstract The invention discloses 7-benzo(c)acridine-p-fluorobenzamidothiourea and its preparation method and application, which has a structural formula: And the application of the present invention in the preparation of antitumor drugs, combined with pharmaceutically acceptable auxiliary materials to make injections, tablets, pills, capsules, suspensions or emulsions; the present invention connects the active The group amidothiourea introduces a fluorine-containing group to enhance the biological activity of the parent ring structure through the principle of active superposition. The antitumor test in vitro shows that the compound has a strong inhibitory effect on the tested tumor cells, and can be further developed as an antitumor drug or a lead compound.
priorityDate 2015-12-02-04:00^^<http://www.w3.org/2001/XMLSchema#date>
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