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filingDate 2015-08-11-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a3023a851e23e044f703234a14118345
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publicationDate 2016-06-15-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber CN-105669532-A
titleOfInvention Nimodipine water-soluble derivatives and their preparation methods and applications
abstract The invention discloses a water-soluble derivative of nimodipine and its preparation method and application, belonging to the technical field of medicinal chemistry. This type of nimodipine water-soluble derivative has the structural characteristics of general formula I, has high water solubility, and can be converted into nimodipine by internal enzymes in the blood or in the body, so this type of nimodipine water-soluble derivative can be used as The nimodipine prodrug is used as a calcium ion antagonist for the treatment of cardiovascular and cerebrovascular diseases.
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priorityDate 2014-12-03-04:00^^<http://www.w3.org/2001/XMLSchema#date>
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