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classificationCPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-137
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classificationIPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-137
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P31-10
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-4196
filingDate 2016-03-29-04:00^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 2018-06-29-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationDate 2018-06-29-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber CN-105663126-B
titleOfInvention The antifungal products of ambroxol hydrochloride joint Fluconazole and its application
abstract Antifungal products and its application the invention discloses ambroxol hydrochloride joint Fluconazole, belong to pharmaceutical technology field, and the present invention studies the static state and dynamic syndicated antifungic action of Fluconazole and ambroxol hydrochloride combination to drug resistance Candida albicans in a variety of ways.Effective concentration when ambroxol hydrochloride is applied with fluconazole matches:Fluconazole:Ambroxol hydrochloride=1:64 (μ g/mL), minimum inhibitory concentration is respectively:128 μ g/mL and 2 μ g/mL.When ambroxol hydrochloride combines Fluconazole, antibacterial activity of the Fluconazole to drug resistance Candida albicans can be enhanced, can generate collaboration antifungic action, and can reversing drug resistance Candida albicans to the drug resistance of Fluconazole, exploitation and old medicine for new drug are new with providing research direction.
priorityDate 2016-03-29-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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