http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-105648010-B
Outgoing Links
Predicate | Object |
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classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12P21-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-461 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P21-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K1-36 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K1-34 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K1-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K1-20 |
filingDate | 2016-02-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2020-08-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2020-08-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CN-105648010-B |
titleOfInvention | Preparation method of hammerhead shark meat antioxidant peptide for activating Nrf2-ARE pathway |
abstract | The invention discloses a preparation method of hammerhead shark meat antioxidant peptide for activating an Nrf2-ARE pathway. The method takes chignon shark meat as a raw material, enzymolysis liquid is obtained through double-enzyme enzymolysis, the enzymolysis liquid is separated and purified by adopting ultrafiltration, macroporous resin purification, gel column chromatography and reversed-phase high performance liquid chromatography to obtain antioxidant peptide Ile-Ile-Gly-Leu-Val-Pro (IIGLVP), and ESI-MS is used for determining the molecular weight of the antioxidant peptide to be 610.77 Da; the prepared high-activity antioxidant peptide has good scavenging effect on DPPH free radicals, hydroxyl free radicals and superoxide anion free radicals; meanwhile, the protein accumulation of the Nrf2 can be promoted, the Nrf2-ARE channel is activated, and the medicine and the functional product can be used for treating liver injury, skin photoaging, arteriosclerosis, apoplexy, diabetes, obesity and other diseases closely related to the Nrf2-ARE channel. |
priorityDate | 2016-02-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 64.