http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-105647845-B
Outgoing Links
Predicate | Object |
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classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12P7-42 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Y101-01008 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-26 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Y102-04002 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-0008 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-0006 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Y402-0103 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-88 |
classificationIPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12R1-19 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P7-42 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N1-21 |
filingDate | 2016-03-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2019-05-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2019-05-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CN-105647845-B |
titleOfInvention | A kind of recombinant Escherichia coli for producing 3-hydroxypropionic acid and its application |
abstract | The invention discloses a recombinant Escherichia coli for producing 3-hydroxypropionic acid and an application thereof. The recombinant Escherichia coli is obtained by dehydrating glycerol dehydratase gene dhaB123, glycerol dehydratase reactivation factor gene gdrA and α-ketoglutarate semialdehyde The hydrogenase mutant encoding gene TUkgsadh and the glycerol triphosphate dehydrogenase encoding gene gpd1 are introduced into the host bacteria and constructed. By using gene knockout technology, the inhibition of glycerol entering and leaving cells is relieved, and the cofactor NAD + of aldehyde dehydrogenase is regenerated at the same time. This results in a 12-fold increase in 3‑HP yield. |
priorityDate | 2016-03-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 142.