Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_4d9dbc2c0705931153800d351be59f09 |
classificationIPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12R1-77 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12R1-885 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12R1-80 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12R1-66 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12R1-645 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N9-42 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N1-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P19-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P19-12 |
filingDate |
2014-11-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_eff4009a6312cdd76c32d8b4979c813b http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_776f4d5b0cd6833d70eaa837da0bf4be http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9103fddc7950f40470dd5ab05fca59d0 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b74ea8a1b2de8ac50d293dc7fdd28b7b http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9fcc0717b2e87e9e9d5ad208ee42e54c http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_be925644465761663b42d4b54e1c4b32 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7eb425aa809f20d17d7913e461ed92e1 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4fe90ec061bd89abf72f892ca3af6685 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0310e545cb9a53895c1c2e6c25afd3a1 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_06ed88bec26b5d18e48f0b5bbd327e1e http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_bcd9063199d61be454b7e155d84c8e4a |
publicationDate |
2016-06-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
CN-105647811-A |
titleOfInvention |
Strain construction method for improving filamentous fungus cellulase yield and degradation capacity of lignocellulose and application of strain construction method |
abstract |
The invention discloses a genetically engineered bacterium for high yield of cellulase and for improvement of degradation capacity of lignocellulose as well as application of the genetically engineered bacterium. A series of multi-gene mutant strains, namely delta 3 beta G delta cdt2 delta ncu05853, delta 2 beta G delta cdt2 delta ncu05853, delta 3 beta G delta cdt2 delta ncu05853 delta cre1 and delta 2 beta G delta cdt2 delta ncu05853 delta cre1, are obtained by discovering the functions of a cello-oligosaccharide transport protein like protein CLP1 (NCU05853) and by further knocking out clp1 and three beta-glucosidase genes NCU00130, NCU04952 and NCU08755, two cello-oligosaccharide transport protein genes NCU00801 (cdt-1) and NCU08114 (cdt-2) and one carbon-decomposed metabolite repressor protein CRE-1 (NCU08807) in a combined mode; and the combined mutant strain can improve the yield of cellulase and the degradation capacity of lignocellulose when cellobiose or lignocellulose serves as a substrate. The invention provides a method which is capable of promoting production of the cellulase and capable of producing chemicals from the lignocellulose. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-109234277-A |
priorityDate |
2014-11-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |