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Predicate Object
classificationCPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D498-10
classificationIPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D498-10
filingDate 2015-12-30-04:00^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 2017-07-28-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationDate 2017-07-28-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber CN-105646532-B
titleOfInvention A kind of synthetic method of diaza spiro [5.6] dodecane of 2 tertbutyloxycarbonyl, 10 carbonyl, 8 oxo 2,11
abstract The present invention relates to the synthetic method of 8 oxo of a kind of 2 tertbutyloxycarbonyl, 10 carbonyl 2,11 diaza spiro [5.6] dodecane.Mainly solve the technical problem of the conversion of overprotection group.Present invention employs the cyano piperidines of 1 N BOC of raw material 3 cheap and easy to get; pass through alkylated reaction; hydrogenation; the oxo 2 of seven steps reaction 2 tertbutyloxycarbonyl of synthesis such as protection group abjection, 10 carbonyl 8; 11 diaza spiros [5.6] dodecane, this route is the synthesis of numerous spiro-compounds there is provided good reference function.
priorityDate 2015-12-30-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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