abstract |
The invention provides a sulfamic acid ester as an indoleamine-2,3-dioxygenase inhibitor, a preparation method and application thereof. The structure of the inhibitor of the present invention is shown in the general formula I, wherein the definitions of X, R 1 , R 2 , R 3 , R 4 , R 5 and n are as shown in the specification and claims. The invention also discloses a preparation method of the inhibitor. The compound of general formula I of the present invention can be used as an indoleamine-2,3-dioxygenase inhibitor for the preparation of a drug for preventing and/or treating diseases mediated by indoleamine-2,3-dioxygenase drug. |