http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-105646344-B
Outgoing Links
Predicate | Object |
---|---|
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D215-18 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D215-18 |
filingDate | 2016-02-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2018-08-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2018-08-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CN-105646344-B |
titleOfInvention | A kind of purification method of montelukast |
abstract | The invention relates to a purification method of montelukast, which comprises adding montelukast solid into ethanol aqueous solution, heating until completely dissolved, slowly cooling down, crystallizing, suction filtration, and washing the filter cake with ethanol aqueous solution; washing liquid and mother liquor are combined and concentrated , crystallization, suction filtration, and washing in the above manner, and the resulting washing liquid was combined with the mother liquor and concentrated to dryness to obtain montelukast solid. The invention has good impurity removal effect and high yield, and is suitable for the purification of montelukast in industrialized production. |
priorityDate | 2016-02-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 33.