| abstract |
The invention discloses a preparation method of formula granules of Longdan Xiegan Decoction. The preparation method comprises: taking gentian, gardenia, scutellaria baicalensis, Alisma, rehmannia glutinosa, plantago seed, angelica, bupleurum, akeba, licorice Add 5-15 times the weight of water to the Shiwei decoction pieces, decoct and extract twice; combine the two decocted filtrates, and concentrate the filtrate under vacuum; the concentrated solution is spray-dried to obtain spray-dried powder, which is pulverized into The superfine powder is obtained by adding the superfine powder into maltodextrin and dry granulating. Its quality control methods include infrared fingerprints, thin-layer qualitative identification and HPLC content determination. The method of the invention can give full play to the advantages of the compatibility of traditional Chinese medicines, and retain the active ingredients to the greatest extent; it has established a perfect quality standard, adopts the one-measurement-multiple-evaluation technology of thin-layer chromatography, and combines infrared spectroscopy and chromatography for quality control, which can effectively control The quality of compound granules. |