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classificationCPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K8-20
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filingDate 2016-01-27-04:00^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 2018-04-24-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationDate 2018-04-24-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber CN-105640788-B
titleOfInvention A kind of hydroxy agustite tooth-paste and preparation method thereof
abstract Hydroxy agustite tooth-paste of the present invention, includes micron order hydroxyapatite, nanometer hydroxyapatite and fluoride;The particle diameter of μ-hydroxyapatite is 0.1 μm~10 μm, and the particle diameter of nanometer hydroxyapatite is less than 100nm;Mass concentration of the fluorine element in hydroxy agustite tooth-paste is not more than 8.0wt% in fluoride, and the mass content of nano-grade hydroxy apatite is not more than 20wt%, and the mass ratio of micron order hydroxyapatite and nanometer hydroxyapatite is 1:10~18:1.For the hydroxy agustite tooth-paste in use, helping demineralization dentine piece to carry out biomineralization, reparation dentine piece, reduces canaliculi dentales aperture, or even blocks dentinal tubule or hydroxyapatite layer is deposited in dentin surface.At the same time, the fluoride hydrolysis generation fluorine ion being adapted to micron order hydroxyapatite, nanometer hydroxyapatite content, promotes the mineralization process of hydroxyapatite in dentine, significantly improves repair function of the hydroxy agustite tooth-paste to dentine.
priorityDate 2016-01-27-04:00^^<http://www.w3.org/2001/XMLSchema#date>
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