http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-105628841-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N30-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N30-88 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N30-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N30-88 |
| filingDate | 2015-12-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2018-02-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2018-02-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-105628841-B |
| titleOfInvention | A kind of method with liquid chromatography for separating and determining Apremilast and its corresponding isomers |
| abstract | The present invention provides a kind of method with liquid chromatography for separating and determining Apremilast and its corresponding isomers, it is related to technical field of analytical chemistry, this method uses surface to be covalently bonded with the silica gel of amylose three (3 meta-chlorocarbanilate) as the chiral chromatographic column of filler, with methyl tertiary butyl ether(MTBE) ethanol diethylamine (91 9 0.1) for mobile phase, flow velocity is 1ml/min, wavelength is 230nm, and column temperature is 30 DEG C.The high performance liquid chromatography separation detection method separating degree of Apremilast of the present invention and its enantiomter is high, specificity is strong, solves the problems, such as Apremilast and its difficult separation of enantiomter, so as to ensure that the quality controllable of Apremilast and its preparation. |
| priorityDate | 2015-12-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 20.