http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-105628797-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N30-02 |
| filingDate | 2014-10-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2017-10-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2017-10-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-105628797-B |
| titleOfInvention | Icodextrin bulk drug molecular weight and its distribution determination method |
| abstract | The present invention relates to pharmaceutical technology field, more particularly to Icodextrin bulk drug molecular weight and its distribution determination method, detected that specific step is as follows using method associated with gel permeation chromatography GPC laser light scattering LS differential detections RI：Sample preparation is taken 100 μ l sample introductions to determine, use gel column SB G for guard column into 10mg/ml solution during measure, the HQ of chromatographic column SB 802 and the HQ of chromatographic column SB 803 series connection, with 0.2 ‰ NaN 3 Acetate buffer is mobile phase, and flow velocity is 0.5ml/min, 30 DEG C of column temperature, 35 DEG C of detection temperature；Record molecular weight and molecular weight distribution.The characteristics of GPC laser light scatterings GC-MS of the present invention has had GPC method and light scattering method concurrently, high molecular heavy, number-average molecular weight can quickly and accurately be determined, and the weight average molecular weight measured is absolute molecular weight, reference substance calibration is not needed, and is realized to Icodextrin absolute molecular weight and its Accurate Determining of distribution. |
| priorityDate | 2014-10-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 15.