http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-105624125-B
Outgoing Links
Predicate | Object |
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classificationIPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12R1-19 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P13-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P13-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N1-21 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-53 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-63 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N9-02 |
filingDate | 2014-11-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2020-03-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2020-03-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CN-105624125-B |
titleOfInvention | Aldehyde and ketone reductase and its application in the synthesis of (2S,3R)-2-benzoylaminomethyl-3-hydroxybutyrate |
abstract | The present invention provides a new mutant of aldo-ketone reductase and a method for asymmetric reduction by using the mutant of recombinant aldo-ketone reductase or its freeze-dried powder. When the substrate concentration is as high as 1000g/L, the optical purity of the product is still as high as more than 98%, and no additional expensive coenzyme is needed. Compared with other asymmetric reduction preparation methods, the product prepared by the method of the present invention has a high concentration, and has the advantages of high optical purity of the product, mild reaction conditions, environmental friendliness, simple operation, and easy industrial scale-up. Therefore, it has the advantages of good industrial application prospects. |
priorityDate | 2014-11-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 353.