http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-105622500-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D215-18 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D215-18 |
| filingDate | 2016-02-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2018-03-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2018-03-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-105622500-B |
| titleOfInvention | The preparation method of montelukast sodium intermediate |
| abstract | The invention relates to a preparation method of a montelukast sodium intermediate. Under the protection of an inert gas, in a solvent, under the action of a catalyst, the montelukast core compound whose secondary hydroxyl group is replaced by various leaving groups undergoes nucleophilic substitution reactions with various side chains to obtain different montelukast The intermediate of sterna, the present invention uses new catalyst: 4-dimethylaminopyridine, 4-pyrrolidinyl pyridine, makes the reaction condition of the present invention gentle, fast, single product, easy and simple to purify, the obtained intermediate optical High purity and high yield, more suitable for industrial production. |
| priorityDate | 2016-02-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 46.