http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-105622480-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_372338508c8646c4a6e59b6be42ccb56 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D207-452 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D207-452 |
| filingDate | 2015-12-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_703f477f5a2b63ed58314942d5e98b83 |
| publicationDate | 2016-06-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-105622480-A |
| titleOfInvention | Synthetic method for furan diamine drug intermediate N-(2-ethoxyl) phthalimide |
| abstract | The invention relates to a synthetic method for furan diamine drug intermediate N-(2-ethoxyl) phthalimide. The synthetic method includes the following steps that 0.43 mol of phthalic anhydride, 0.05 mol of cuprous chloride, 300 ml of pyridine and 0.44-0.46 mol of ethanol hydroxylamine are added into a reaction vessel provided with a stirrer, a thermometer and a reflux condenser, the solution temperature is slowly raised, a reflux reaction is conducted for 3-4 h at the temperature of 205 DEG C-215 DEG C, the solution temperature is reduced to 10 DEG C-minus 15 DEG C to separate a solid, the solid is added into 500 ml of a xylene solution, the solution temperature is reduced to 3 DEG C-minus 5 DEG C to separate a solid, the solid is sequentially washed with a salt solution, dehydrated with a dehydrating agent and recrystallized in ethyl acetate to obtain a white solid N-(2-ethoxyl) phthalimide. In the steps, the mass fraction of pyridine is 85-90%, and the mass fraction of the xylene solution is 55-60%. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-106632444-A |
| priorityDate | 2015-12-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 47.