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Outgoing Links

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classificationCPCAdditional http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2760-16022
classificationCPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-4711
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-005
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C201-08
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C205-44
classificationIPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-11
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K1-04
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http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-47
filingDate 2016-02-06-04:00^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 2018-08-03-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationDate 2018-08-03-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber CN-105622424-B
titleOfInvention Compound and its preparation method and application
abstract The present invention relates to compounds and its preparation method and application, specifically, provide a kind of 5 nitrobenzaldehyde derivative of 2 hydroxyl, are compound shown in formula (I), wherein R 1 For H or methyl;R 2 For H, C 1‑6 Alkyl or C 6‑10 Aryl;R 3 For H, C 1‑6 Alkyl or C 6‑10 Aryl.In polypeptide preparation process, it can break the interaction between chain amino acids residues using the compound, and then the formation of the secondary structure of polypeptide chain can be inhibited, break the interaction of hydrogen bond between carbonyl and amino, reduce the generation of clustering phenomena during Peptide systhesis, so that the synthesis of slightly solubility polypeptide fragment, isolating and purifying and to characterize process similar with conventional water soluble polypeptide, so as to efficiently prepare difficult sequences polypeptide.
priorityDate 2016-02-06-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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