http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-105601472-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C67-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C67-307 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C67-343 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C51-09 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07F5-025 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C63-36 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C67-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07F5-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C27-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C67-343 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C67-307 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C69-76 |
| filingDate | 2016-01-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2017-11-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2017-11-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-105601472-B |
| titleOfInvention | The preparation method of novel 5-[4-(1-carboxynaphthyl)]-isophthalic acid |
| abstract | The preparation method of 5-[4-(1-carboxynaphthyl)]-isophthalic acid, 4-naphthoic acid generates compound A through methylation reaction: 4-bromo-naphthoic acid methyl ester; 5-amino-m-benzene Dimethyl dicarboxylate undergoes diazotization and bromination reaction to generate compound B: 5‑bromo‑dimethyl isophthalate; under nitrogen protection conditions, a catalyst is added to allow it to undergo Miyaura boronate esterification with biboronic acid pinacol ester The reaction generates compound C: 3,5-dimethoxycarbonylphenylboronic acid pinacol ester; A and C react under nitrogen protection under the catalyst to generate compound D: 5-[4-(1-methoxycarbonylnaphthyl)]- Dimethyl isophthalate; the target compound E: 5-[4-(1-carboxynaphthyl)]-isophthalic acid is generated through hydrolysis. The method has the advantages of simple synthesis method, low synthesis cost, high yield and high product purity. The target compound E is as follows: . |
| priorityDate | 2016-01-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 99.