http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-105586355-B
Outgoing Links
Predicate | Object |
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classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y02P20-52 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12P21-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12P21-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-88 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-58 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-80 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-242 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-2414 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Y401-01023 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Y302-01001 |
classificationIPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12R1-77 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-55 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-60 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N1-15 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-80 |
filingDate | 2009-09-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2020-05-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2020-05-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CN-105586355-B |
titleOfInvention | Methods of producing polypeptides in enzyme-deficient mutants of Fusarium venenatum |
abstract | The present invention relates to a method of producing a polypeptide in an enzyme-deficient mutant of Fusarium venenatum, in particular to a method of producing a polypeptide, comprising: (a) culturing a parental Fusarium venenatum strain in a medium for producing the polypeptide , wherein the mutant strain comprises a polynucleotide encoding the polypeptide and one or more (several) genes selected from the group consisting of pyrG, amyA and alpA, wherein the one or more (several) genes each) genetically modified such that said mutant strain is deficient in the production of one or more (several) enzymes selected from the group consisting of whey, respectively, compared to the parental Fusarium venenatum strain grown under the same conditions glycoside-5'-monophosphate decarboxylase, alpha-amylase, and alkaline protease; and (b) recovering the polypeptide from the culture medium. The present invention also relates to enzyme-deficient mutants of Fusarium venenatum strains and methods of producing such mutants. |
priorityDate | 2008-09-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 397.