http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-105567839-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-686 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-686 |
| filingDate | 2016-02-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2019-02-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2019-02-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-105567839-B |
| titleOfInvention | The colorimetric method of enzyme circulation amplification detection DNA based on network-type nucleic acid nano probe |
| abstract | The present invention provides the colorimetric methods of the enzyme circulation amplification detection DNA based on network-type nucleic acid nano probe.Amplifying technique is recycled using aptamer self assembly network-type nucleic acid nano probe and enzyme, to reach the trace detection to target DNA.Its design principle are as follows: separately design the end of trident DNA1 and trident DNA2 makes two kinds of trident DNA by interconnecting with the specific recognition of fibrin ferment to be capable of the aptamer sequence 1 of specific recognition fibrin ferment and aptamer sequence 2, forms network structure.Wherein, aptamer sequence 1 and aptamer sequence 2 are again rich G sequence, a large amount of Mimetic Peroxidases can be formed in conjunction with hemin, catalysis reaction substrate generates the detection signal of amplification.By this method, it can be achieved that the ultra-high sensitive to target DNA detects, it is not necessarily to complex instrument equipment, it is simple and easy. |
| priorityDate | 2016-02-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 81.