http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-105566398-B
Outgoing Links
Predicate | Object |
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classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07F15-008 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-555 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07F15-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 |
filingDate | 2015-12-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2018-04-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2018-04-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CN-105566398-B |
titleOfInvention | A kind of oxide of high activity aporphine alkali rhodium (III) complex and its synthetic method and application |
abstract | The invention discloses a kind of oxide of high activity aporphine alkali rhodium (III) complex and its synthetic method and application.The complex can be synthesized using three kinds of different methods.The method of three kinds of synthesis of the present invention is gradually become simple by complexity, and the synthetic method of existing oxidation aporphine alkali metal complex is entirely different therewith.Applicant also investigates the inhibitory action of part OGC, oxidation glaucine rhodium (III) complex and complex of the present invention to various tumor cell strains, and antitumor activity inside complex of the present invention, as a result finds:Compared with part OGC and oxidation glaucine rhodium (III) complex, complex of the present invention shows the in vitro and in vivo antitumor activity significantly increased, far above the antitumor activity of existing other oxidation glaucine metal complexs.Shown in oxide of high activity aporphine alkali rhodium (III) complex structure formula of the present invention such as following formula (I): |
priorityDate | 2015-12-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 70.