http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-105566349-A

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classificationIPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D499-76
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D499-12
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D499-20
filingDate 2014-11-10-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e02d1a753d3f411ff86195d31c539150
publicationDate 2016-05-11-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber CN-105566349-A
titleOfInvention Synthesis process of o-chloro-benzathine penicillin
abstract The invention discloses a synthesis process of o-chloro-benzathine penicillin. 6-aminopenicillanic acid is firstly dissolved in a dilute alkali solution to be prepared into sodium salt in an aqueous solution of an organic solvent, then subjected to condensation with isoxazolyl o-chlorobenzoyl chloride to directly obtain a cloxacillin sodium solution, and the cloxacillin sodium solution is subjected to double decomposition reaction with N, N-dibenzyl ethylenediamine diacetate to obtain the o-chloro-benzathine penicillin. The synthesis process of the o-chloro-benzathine penicillin disclosed by the invention has benefits of simple process, simple and convenient operation, low cost and easy industrial production.
isCitedBy http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-106883249-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-110452254-A
priorityDate 2014-11-10-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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