http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-105566349-A
Outgoing Links
Predicate | Object |
---|---|
assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_67749b352cf78b8d1a7f7c346e880393 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D499-76 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D499-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D499-20 |
filingDate | 2014-11-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e02d1a753d3f411ff86195d31c539150 |
publicationDate | 2016-05-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CN-105566349-A |
titleOfInvention | Synthesis process of o-chloro-benzathine penicillin |
abstract | The invention discloses a synthesis process of o-chloro-benzathine penicillin. 6-aminopenicillanic acid is firstly dissolved in a dilute alkali solution to be prepared into sodium salt in an aqueous solution of an organic solvent, then subjected to condensation with isoxazolyl o-chlorobenzoyl chloride to directly obtain a cloxacillin sodium solution, and the cloxacillin sodium solution is subjected to double decomposition reaction with N, N-dibenzyl ethylenediamine diacetate to obtain the o-chloro-benzathine penicillin. The synthesis process of the o-chloro-benzathine penicillin disclosed by the invention has benefits of simple process, simple and convenient operation, low cost and easy industrial production. |
isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-106883249-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-110452254-A |
priorityDate | 2014-11-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 38.