http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-105548378-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2030-027 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N30-02 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N30-02 |
| filingDate | 2015-12-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2017-12-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2017-12-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-105548378-B |
| titleOfInvention | A kind of canagliflozin α, the separation method of beta isomer |
| abstract | The invention discloses a kind of canagliflozin α, the separation method of beta isomer, and using high performance liquid chromatograph, using C18 posts as chromatographic column, for the mixed liquor formed using acetonitrile and water as mobile phase, the flow velocity for controlling mobile phase is 0.80~1.20mL/min；Chromatogram column temperature is 20~40 DEG C；Sample size is 10 μ L；Detection wavelength carries out chromatographic isolation under conditions of being 210nm；The mobile phase calculates by volume, acetonitrile: water is 38~47: 53~62, and the compound of first appearance is canagliflozin beta isomer, and the compound of rear appearance is canagliflozin αisomer.The present invention effectively realizes canagliflozin α, the separation of beta isomer and measure, and its separating degree is up to 1.35~3.95. |
| priorityDate | 2015-12-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 24.