http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-105548335-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N27-62 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N27-62 |
| filingDate | 2016-02-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2018-11-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2018-11-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-105548335-B |
| titleOfInvention | A method for rapid detection of nicotine and cotinine in neonatal meconium |
| abstract | The invention discloses a method for quickly detecting the content of nicotine and cotinine in neonatal meconium. The cotinine isotope internal standard methanol solution is used as an extraction ionization reagent to ionize the sample and generate a spray so that the center line of the mass spectrometer is parallel to the toothpick with a distance of 0.5-5 cm; turn on the mass spectrometry system and set it to positive ion mode. The advantage of the present invention is that: the method of the present invention simplifies the pretreatment process of samples, without sample pretreatments such as extraction and chromatographic separation, and uses medical cotton swabs to wipe electrospray mass spectrometry to conduct direct ionization mass spectrometry analysis on newborns, which greatly simplifies the entire analysis Process, medical cotton swabs are clean and hygienic, especially suitable for clinical mass analysis. The sample pretreatment steps are simplified for direct ionization, which greatly improves the accuracy and precision of the determination. |
| priorityDate | 2016-02-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 18.