http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-105541831-B
Outgoing Links
Predicate | Object |
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classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D455-03 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-4375 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P37-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D455-03 |
filingDate | 2016-01-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2017-05-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2017-05-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CN-105541831-B |
titleOfInvention | Medicine root berberrubine derived from amur cork-tree processed product and separation preparation method and application thereof |
abstract | The invention provides medicine root berberrubine derived from an amur cork-tree processed product and a separation preparation method and application thereof. The method includes the steps that 1, jatrorrhizine hydrochloride reference substances are precisely weighed, placed in an evaporation dish to be baked, taken out and cooled, chromatographic grade methyl alcohol is added, millipore filter filtering is conducted, and a baked jatrorrhizine reference substance solution is obtained; 2, the baked jatrorrhizine reference substance solution is separated through a preparative liquid phase, eluant of a target chromatographic peak is collected and purified through a sephadex column, the purified eluant is subjected to nitrogen blowing and freeze drying, and pink powder, namely, medicine root berberrubine crystals prepared through separation are obtained. The prepared medicine root berberrubine is a new compound found in amur cork-tree processed decoction pieces, the separation preparation method has the advantages of being high in efficiency, stable in process, easy and convenient to operate and low in cost, high-purity separation preparation of a large number of medicine root berberrubine monomers can be achieved, and the medicine root berberrubine compound has good macrophage phagocytosis and high immunization. |
priorityDate | 2016-01-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 46.