| abstract |
The invention discloses the application of a substituted aromatic amide or a nitrogen-containing heterocyclic compound in the preparation of a monoamine oxidase inhibitor. The structural formula of the substituted aromatic amide or a nitrogen-containing heterocyclic compound is as follows: (I), (II), (III) , (IV), (V), (VI), (VII) or (VIII): In formula (I), m is the natural number between 1～4; R 1 is selected from H or Wherein R 2 and R 3 are each independently H, amino, C1-C4 alkoxy or halogen; Ar is selected from one of the following groups: Wherein R 4 is H, halogen or trifluoromethyl; In formula (II), R 5 is trifluoromethyl or C1-C4 alkyl; R 6 is H, R 7 is cyclohexyl, or R 6 and R 7 are ring-fused to form a piperidine ring; In formula (III), n is 0 or 1 , and R is or Wherein R 9 is an amino group, R 10 is a C1-C4 alkyl group; or n is a natural number between 1 and 4, and R 8 is H; |