abstract |
The invention relates to a continuous separation and purification technology of gentamycin C1a. Efficient separation of a gentamycin C1a recovered liquid is realized through using a continuous chromatographic separation technology. The technology comprises the following steps: allowing recovered gentamycin C1a to enter a continuous chromatographic system, adsorbing, washing out impurities, eluting, collecting the obtained eluate, regenerating a chromatographic column, and concentrating the collected eluate to obtain gentamycin C1a. The gentamycin C1a separated in through the technology has the advantages of high yield and high purity, so the technology has the advantages of low cost, environmental protection and suitableness for industrial production. |