http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-105503840-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D405-14 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D405-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P25-28 |
| filingDate | 2015-12-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2019-02-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2019-02-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-105503840-B |
| titleOfInvention | A kind of Tacrine-coumarin derivative and its application containing triazol radical |
| abstract | Tacrine-the coumarin derivative and its application that the present invention relates to a kind of containing triazol radical, belong to biomedicine technical field；The derivative includes compound of formula I and pharmaceutically useful salt, and preparation method includes 3 kinds；Confirm that such compound is acetylcholinesterase inhibitor through pharmacological testing, it is able to suppress acetylcholinesterase, the activity of BuChE and ammoxidation single enzyme (MAO) activity, it is able to suppress the auto polymerization of beta-amyloid protein simultaneously, delay the hydrolysis of acetylcholine and the auto polymerization of beta-amyloid protein, acetylcholine is improved in the effect of cynapse, can be effectively used for treatment azheimer's disease. |
| priorityDate | 2015-12-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 170.