http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-105503831-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C09K2211-1029 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C09K2211-1044 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C09K2211-1007 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D401-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D209-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C09K11-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K49-0032 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N21-64 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N21-359 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N21-359 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K49-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D401-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D209-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N21-64 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C09K11-06 |
| filingDate | 2015-12-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2018-12-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2018-12-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-105503831-B |
| titleOfInvention | A kind of near infrared fluorescent probe and its preparation method and application with the response of pole acid pH |
| abstract | The present invention provides a kind of near infrared fluorescent probes with the response of pole acid pH, shown in chemical structural formula such as formula (I): In formula, X is-C (CH 3 ) 2 ,-O- ,-S- or-Se-, Z be Or with-R'NH 2 Shown in group, wherein R' C 1‑12 Alkylidene, R 1 And R 2 Separately it is selected from H atom, C 1‑18 Alkyl or with-SO 3 R 5 Shown in group, wherein R 5 For C 1‑18 Alkyl or benzyl, R 3 And R 4 Separately it is selected from C 1‑18 Alkyl or benzyl, Y F, Cl, Br or I.The near infrared fluorescent probe has lower pKa value, to H + Having higher sensitivity, highly selective, stocks to be displaced, larger, background interference is small, smaller to cell and living body injury, is well suited for the detection for carrying out pH under the acid environment of pole, overcomes the defect of prior art fluorescence probe.The present invention also provides the preparation method and applications of the probe. |
| priorityDate | 2015-12-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 40.