http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-105503752-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D243-38 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D243-38 |
| filingDate | 2016-02-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2018-09-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2018-09-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-105503752-B |
| titleOfInvention | A kind of method that catalysis prepares 1,5- benzodiazepine * analog derivatives |
| abstract | The invention discloses a kind of methods that catalysis prepares 1,5 benzodiazepine * analog derivatives, belong to ionic liquid-catalyzed technical field.The molar ratio of o-phenylenediamine, 5 in preparation reaction, 5 dimethyl, 1,3 cyclohexanedione and aromatic aldehyde is 1：1：1, the mole of acidic ionic liquid catalysts is the 10~15% of aromatic aldehyde used, the volume that 85% ethanol water of reaction dissolvent is counted using milliliter as aromatic aldehyde by mM in terms of 5~8 times of amount of substance, reflux time is 10~20min, it is cooled to room temperature after reaction, it filters, 1,5 benzodiazepine * analog derivatives is obtained after filter residue vacuum drying.The present invention has the characteristics that catalyst biodegradable is good, raw material availability is high and whole preparation process is simple to operate compared with using the preparation method of other acidic ionic liquid catalysts, convenient for industrialization large-scale application. |
| priorityDate | 2016-02-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 65.